Occludin and Zonulin in Attention-deficit/Hyperactivity Disorder

Ataturk University

Status: Completed

Conditions: Attention-deficit/Hyperactivity Disorder

Treatments: Diagnostic Test: Occludin; Diagnostic Test: Zonulin

Study type: Interventional

Funder types: Other

Identifiers

NCT05502471

025

Details and patient eligibility

About

The association between levels of zonulin and occludin and behavioral/emotional problems in children with ADHD are investigated.

Full description

Inclusion criteria for the ADHD group are (a) newly diagnosed ADHD (b) no prior psychotropic treatment for ADHD or any psychiatric disorder (c) age 6-12 years. Exclusion criteria were: (a) history of history of inflammatory/noninflammatory, metabolic, or autoimmune disease (b) any special diet history within the past year (c) use of corticosteroids or regular intake of medication in the last 6 months, (d) body mass index (BMI) [kg/m2] > 30), and (e) cognitive deficits by developmental history.

Enrollment: 79 patients

Sex: All

Ages: 6 to 12 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• (a) newly diagnosed ADHD
• (b) no prior psychotropic treatment for ADHD or any psychiatric disorder
• (c) age 6-12 years.

Exclusion criteria

• (a) history of history of inflammatory/noninflammatory, metabolic, or autoimmune disease
• (b) any special diet history within the past year
• (c) use of corticosteroids or regular intake of medication in the last 6 months,
• (d) body mass index (BMI) [kg/m2] > 30),
• (e) cognitive deficits by developmental history

Trial design

Primary purpose: Diagnostic

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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79 participants in 2 patient groups

ADHD

Other group

Description:

Children with ADHD

Treatment:

Diagnostic Test: Zonulin

Diagnostic Test: Occludin

Control

Other group

Description:

Children without any psychiatric disorder

Treatment:

Diagnostic Test: Zonulin

Diagnostic Test: Occludin