Occupational Cataracts and Lens Opacities in Interventional Cardiology : the O'CLOC Study

Sophie JACOB

Status: Completed

Conditions: Cataracts; Lens Opacities

Study type: Observational

Funder types: Other

Identifiers

NCT01061463

IRSN-09079

Details and patient eligibility

About

The purpose of this study is to test the existence of an increased risk of cataracts among interventional cardiologists as compared to cardiologists not exposed to X-rays.

Full description

This cross-sectional study includes cardiologists aged > 40 years: a group of interventional cardiologists (coronary interventionists and electrophysiologists) and a group of unexposed workers (including cardiologists). Individual information, including risk factors of cataracts (age, diabetes, myopia, etc. ...), are collected during a telephone interview. For the exposed group, a specific section of the questionnaire is focused on the occupational history, the description of the procedures (type, frequency, radiation protection tool) and will be used for the classification into "comparable exposure level" groups according to estimates of cumulative dose. For all participants, eye examinations are performed to specifically detect cataracts even in the early stages (lens opacities, LOCS III according to the international standard classification).

Enrollment: 250 patients

Sex: All

Ages: 40 to 75 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• aged at least 40 yrs old
• for interventional cardiologists: cumulated number of procedures > 2000

Exclusion criteria

• previous history of medical radiation exposure for radiotherapy or brain scans
• for non-interventional cardiologists: occupational history of interventional cardiologist

Trial design

250 participants in 2 patient groups

Exposed group

Description:

French coronary interventional cardiologists and cardiologists specializing in cardiac arrhythmias treatments (electrophysiologists), occupationally exposed to X-Rays

Unexposed group

Description:

French non-interventional cardiologists and non medical workers, not occupationally exposed to X-Rays