OCT Imaging of Papilledema in Pediatric Idiopathic Intracranial Hypertension

Hillel Yaffe Medical Center

Status: Unknown

Conditions: Pediatric Idiopathic Intracranial Hypertension

Treatments: Other: OCT Imaging

Study type: Interventional

Funder types: Other

Identifiers

NCT02665858

0035-15-HYMC

Details and patient eligibility

About

Longitudinal clinical observation of optic nerve head, using slit lamp fundoscopy, guides therapy in pediatric idiopathic intracranial hypertension (IIH) patients; however, it remains a limited method of producing quantitative data in evaluating in patients with IIH.

In this study we intend to compare, by using spectral domain optical coherence tomography (OCT), the mean retinal nerve fiber layer thickness and total retinal thickness (RNFLT/TRT) of the optic nerve of newly diagnosed IIH children to a control group. This will provide a quantitative measure for follow-up and treatment of this patient group.

Enrollment: 50 estimated patients

Sex: All

Ages: 5 to 18 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Children with suspected IIH

Exclusion criteria

• Retinal disease
• High refractive error
• Unable to undergo OCT imaging

Trial design

Primary purpose: Diagnostic

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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50 participants in 2 patient groups

IIH Patients

Active Comparator group

Description:

Patients diagnosed with Idiopathic Intracranial Hypertension who undergo OCT imaging

Treatment:

Other: OCT Imaging

Control Group

Active Comparator group

Description:

Patients diagnosed with headache with ruled out Idiopathic Intracranial Hypertension who undergo OCT imaging

Treatment:

Other: OCT Imaging