OCT Technology Development to Assess Ocular Integrity and Characterize Ocular Integrity and Intraocular Scatterers

Duke University

Status: Completed

Conditions: Uveitis

Treatments: Device: hand-held swept source optical coherence tomography

Study type: Interventional

Funder types: Other

Identifiers

NCT03531853

Pro00092968

Details and patient eligibility

About

The purpose of this study is to develop and demonstrate new technologies that will enable a non-contact, compact eye imaging system based on OCT to assist an early responder in acute care settings (like an emergency room) to help assess eye trauma and inflammation (swelling inside the eye).

Enrollment: 14 patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Pre-clinical: employees or students (over the age of 18) of the Duke Eye Center or Biomedical Engineering willing to be imaged with OCT system

• Pilot (ER): patients (over the age of 18) presenting emergently to the Duke Emergency room with traumatic eye injuries and/or suspected open globe

• Pilot (Uveitis): patients presenting to the Duke Eye Center with active uveitis and microhyphema or hyphema; patients who have independently consented to undergo vitreous tap or biopsy for their uveitis care at the Duke Eye Center

Exclusion criteria

• Pre-clinical: subject cannot be a direct report to any of the PIs or other key personnel of this study

• Pilot (ER): hemodynamically unstable, unable to consent

• Pilot (Uveitis): unable to consent; cornea or lens opacity/scar which would block the imaging modality

Trial design

Primary purpose: Device Feasibility

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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14 participants in 1 patient group

Imaging patients

Experimental group

Description:

Get uveitis patients and ER patients to image their eyes

Treatment:

Device: hand-held swept source optical coherence tomography