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OCTA and Retinal Angiomatous Proliferation

F

Federico II University

Status

Completed

Conditions

Age Related Macular Degeneration

Treatments

Diagnostic Test: optical coherence tomography angiography

Study type

Observational

Funder types

Other

Identifiers

NCT04689789
2912/20

Details and patient eligibility

About

To investigate, using optical coherence tomography angiography, the retinal vascular features in patients affected by RAP.

Full description

Retinal vascular anomalous complex represents a distinct form of neovascularization in patients with age-related macular degeneration.

The study investigated the changes in retinal vascular network using optical coherence tomography angiography, a novel and non invasive diagnostic technique that allows to better understand the pathophysiologic mechanism of this neovascularization.

Enrollment

118 patients

Sex

All

Ages

65 to 80 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • age older than 65 years
  • diagnosis of retinal angiomatous proliferation and reticular pseudodrusen
  • absence of previous ocular surgery, congenital eye disease, high myopia (>6 dioptres), actual or previous diagnosis of glaucoma, optic disc anomaly, macular or vitreoretinal diseases.
  • absence of significant lens opacities, low-quality OCT-A images.

Exclusion criteria

  • age older than 80 years
  • absence of diagnosis of retinal angiomatous proliferation and reticular pseudodrusen
  • presence of previous ocular surgery, congenital eye disease, high myopia (>6 dioptres), actual or previous diagnosis of glaucoma, optic disc anomaly, macular or vitreoretinal diseases.
  • presence of significant lens opacities, low-quality OCT-A images.

Trial design

118 participants in 3 patient groups

Patients with RAP
Description:
Patients with previous diagnosis of retinal angiomatous proliferation
Treatment:
Diagnostic Test: optical coherence tomography angiography
Patients with reticular pseudodrusen
Description:
Patients with previous diagnosis of reticular pseudodrusen
Treatment:
Diagnostic Test: optical coherence tomography angiography
Control group
Description:
Healthy eyes without actual and previous ocular diseases
Treatment:
Diagnostic Test: optical coherence tomography angiography

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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