Ocular Hypertension And Yoga Study (OHAYS)

Johns Hopkins University

Status

Withdrawn

Conditions

Ocular Hypertension

Depression

Sleep Disturbance

Anxiety

Stress

Treatments

Behavioral: Yoga Intervention

Study type

Interventional

Funder types

Other

Identifiers

NCT01446588

NA_00041019

Details and patient eligibility

About

The investigators aim to pilot test the efficacy of a yoga intervention designed specifically for individuals with ocular hypertension. The investigators would like to find out if a combination of breathing, postures and meditation may help to reduce intraocular pressure in the short term after each yoga session, and also long-term across an 8-week program. Subjects will participate in the yoga intervention sessions led by Dr. Pamela Jeter once a week at the investigators center, and will be asked to practice at home at least twice a week using a audio CD.

Sex

All

Ages

18 to 90 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

Age 18+
Diagnosis of ocular hypertension not requiring treatment of IOP
IOP in at least one eye ≥ 21 mm Hg
Normal Humphrey 24-2 or 30-2 visual fields for both eyes as determined by the patient's glaucoma specialist
Best-corrected visual acuity better than 20/40 in both eyes
Being healthy to the extent that participation in yoga therapy would not exacerbate any existing disease conditions;
Participants do not engage in athletic activity on a regular basis (i.e. are sedentary)
Able and willing to participate on a weekly basis for the 11-week intervention;
Informed consent

Exclusion criteria

VISUAL HISTORY

Any visual field loss in either eye consistently detected with Humphrey Visual Field 30-2 or 24-2
Inability to understand study procedures or communicate responses to visual stimuli in a consistent manner (cognitive impairment)
Previous intraocular surgery, except for uncomplicated extracapsular cataract extraction with posterior chamber-intraocular lens implant and no escape of vitreous to the anterior chamber, strabismus, cosmetic eyelid surgery, and radial keratotomy
Secondary causes of elevated IOP, including ocular and systemic corticosteroid use
Angle closure glaucoma or anatomically narrow angles-75% of the circumference of the angle must be grade 2 or more by Shaffer criteria
Pigmentary glaucoma
Congenital glaucoma
Other diseases that cause visual field loss or optic disc abnormalities
Difference in cup-disc ratios (horizontal by contour) between the two eyes of >0.2
Background diabetic retinopathy, defined as at least 1 microaneurysm seen on ophthalmoscopy with dilated pupil, or any retinal hemorrhage

SPECIFIC SYSTEMIC DISEASES/CONDITIONS

Abdominal Aneurism
Cancer, metastatic
Fibromyalgia, severe
Inflammatory autoimmune diseases (e.g. Lupus, Rheumatoid arthritis, Scleroderma)
Other disabling chronic conditions (e.g., disabling heart or lung disease, diabetic neuropathy, receiving treatment for hepatitis)
A life-threatening or debilitating disease

BACK PROBLEM OF COMPLICATED NATURE, INCLUDING MEDICO-LEGAL ISSUES

Seeking/receiving compensation/litigation for back pain
Previous back surgery, ever
Low back pain that has lasted > 1 month
Severe pain when bending or twisting spine
Sciatica
Discitis or Disk disease
Fracture of vertebra
Infectious cause of back pain
Scoliosis, severe or progressive
Spinal stenosis
Spondylolisthesis
Anklyosing spondylitis

CONDITIONS THAT MIGHT MAKE IT DIFFICULT TO ATTEND THE CLASSES OR PRACTICE AT HOME.

Deafness or severe hearing problems
Psychoses, major
Schedules do not permit participation in classes or home practice (including planning to move out of town)
Paralysis
Unable to walk two city blocks
Unable to get up and down from floor
Lack of transportation
Any planned surgery during the upcoming study period

CONDITIONS/CIRCUMSTANCES THAT MIGHT CONFOUND TREATMENT EFFECTS OR INTERPRETATION OF DATA