Ocular Penetration of Topical Tacrolimus Eye Drops

The Eye Center and The Eye Foundation for Research in Ophthalmology

Status: Unknown

Conditions: Ocular Penetration of Topical Tacrolimus

Treatments: Drug: Tacrolimus

Study type: Interventional

Funder types: Other

Identifiers

NCT02794610

2015-01(P)

Details and patient eligibility

About

Investigators aim to evaluate the ocular penetration of topical tacrolimus 0.03% eye drops.

Topical tacrolimus 0.03% will be instilled into the eyes of patients 15 minutes before cataract surgery. Aqueous samples will be collected at the time of cataract surgery and will be subjected to detection of presence and level of tacrolimus.

Enrollment: 10 estimated patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• Any age or gender
• Patients scheduled for routine cataract surgery
• Clear healthy cornea

Exclusion criteria

• Corneal pathology
• Ocular surface disease
• Intraocular inflammation

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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10 participants in 1 patient group

Topical tacrolimus

Experimental group

Description:

Ten patients will be include. Topical tacrolimus 0.05% will be instilled into the eyes of patients 15 minutes before cataract surgery. Aqueous samples will be collected at the time of cataract surgery and will be subjected to detection of presence and level of tacrolimus.

Treatment:

Drug: Tacrolimus