Ocular Pressure in Steroid-treated Dermatology Patients

University Hospitals Coventry and Warwickshire NHS Trust

Status

Terminated

Conditions

Intra-ocular Pressure

Topical Corticosteroid-treated Dermatology Patients

Treatments

Drug: Potent topical steroid

Drug: Superpotent topical steroid

Study type

Observational

Funder types

Other

Identifiers

NCT01759914

YM076710

Details and patient eligibility

About

Ocular hypertension and glaucoma are eye conditions associated with abnormally high fluid pressure in the eye (called intraocular pressure or IOP). If left untreated, the elevated IOP may eventually cause damage to the nerve of the eye and potential impairment of vision.

The use of certain drugs has been identified as a risk factor for raised IOP, including various forms of administration of corticosteroids. Corticosteroids can also lead to cataract, which is clouding of the lens in the eye that can affect vision.

In this research study, we would like to find out whether the use of corticosteroids in our dermatology clinic leads to raised IOP, in order to identify patients at risk and to allow them to be more closely monitored than others. It is important to identify those patients who have a corticosteroid-induced pressure rise early enough to prevent them from permanent glaucomatous visual loss.

Enrollment

25 patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

patients on whom corticosteroid treatment is being introduced for a duration of at least 12 weeks

Exclusion criteria

pregnant women
patients already under glaucoma treatment
patients unable to give informed written consent or those unable to cooperate fully with the assessments