Ocular Responses to Short and Long-term Lens Wear

Bausch + Lomb

Status: Completed

Conditions: Ametropia

Treatments: Device: Purevision Lenses with ReNu Multiplus; Device: Purevision Lenses with Optifree RepleniSH

Study type: Interventional

Funder types: Industry

Identifiers

NCT00722891

P/289/07/B

Details and patient eligibility

About

The purpose of this study was to determine whether ocular surface sensitivity to pneumatic, mechanical and chemical stimulation would be affected by the use of the combination of a specific silicone hydrogel lens material with two lens care products over a four week period.

Enrollment: 30 patients

Sex: All

Ages: 17+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Is at least 17 years old and has full legal capacity to volunteer;
• Is correctable to a visual acuity of 6/7.5 (20/25) or better (both eyes) with their habitual vision correction;
• Is a current soft lens wearer and wears contact lenses six or more days/week;
• Has clear corneas and no active ocular disease.

Exclusion criteria

• Has any clinically significant blepharitis or dry eye;
• Has undergone corneal refractive surgery;
• Is aphakic;
• Has any active ocular disease;
• Has any systemic disease affecting ocular health;
• Is using any systemic or topical medications that may affect ocular health;

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Double Blind

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30 participants in 2 patient groups

Purevision Lens with ReNu

Active Comparator group

Description:

Purevision Lenses with ReNu Multiplus Solution

Treatment:

Device: Purevision Lenses with ReNu Multiplus

Purevision Lenses with RepleniSH

Active Comparator group

Description:

Purevision Lenses with Optifree RepleniSH Solution

Treatment:

Device: Purevision Lenses with Optifree RepleniSH