Ocular Surface Disease and IOP Monitoring With Travoprost Without Conservatives

Democritus University of Thrace

Status: Completed

Conditions: Glaucoma; Ocular Surface Disease; Glaucoma; Drugs

Treatments: Diagnostic Test: Schirmer Test; Diagnostic Test: Intraocular pressure (IOP); Diagnostic Test: Visual Fields and OCT RNFL; Diagnostic Test: Conjuctival Hyperemia; Diagnostic Test: Tear Break-up Time (TBUT)

Study type: Observational

Funder types: Other

Identifiers

NCT05319470

ES3/Th11/03-02-2022

Details and patient eligibility

About

Primary objective of this study is to study the efficacy of travoprost without preservatives in the treatment of glaucoma patients and to monitor the ocular surface.

Full description

This is a prospective study including patients visiting the outpatient glaucoma clinic of the University General Hospital of Alexandroupolis for their standard evaluation. Study population is already under treatment with a travoprost preparation without preservatives. They will be fully informed about the procedure and the purpose of the study and a written consent will be obtained. For every patient included in the study intraocular pressure will be measured using a Goldman applanation tonometer, according to the standard way of practice at our clinic. Also, Tear Break-Up-Time (BUT), conjunctival hyperemia grading and Schirmer testing will be used to assess the ocular surface state. Visual field tests and OCT RNFL measurements will also be obtained. The above measurements will be repeated 6 months after the initial examination.

Enrollment: 25 patients

Sex: All

Ages: 35 to 90 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients with glaucoma treated with travoprost without preservatives.

Exclusion criteria

• Co-administration of another anti-glaucoma preparation with or without preservatives, Sjogren's syndrome, poor eyelid occlusion of any etiology.

Trial design

25 participants in 1 patient group

Study Group

Description:

100 patients with diagnosed glaucoma receiving travoprost without preservatives

Treatment:

Diagnostic Test: Conjuctival Hyperemia

Diagnostic Test: Schirmer Test

Diagnostic Test: Intraocular pressure (IOP)

Diagnostic Test: Visual Fields and OCT RNFL

Diagnostic Test: Tear Break-up Time (TBUT)