Ocular-vestibular Biomarker Identification for ADHD

Sync-Think

Status: Unknown

Conditions: ADHD, Predominantly Hyperactive - Impulsive; ADHD - Combined Type; ADHD Predominantly Inattentive Type; ADHD

Treatments: Device: EYE-SYNC

Study type: Observational

Funder types: Other; Industry

Identifiers

NCT04504890

EYESYNCOBIADHD2020

Details and patient eligibility

About

This study intends to establish a relationship between oculovestibular eye tracking measures, measures of ADHD, and medication prescribed for ADHD.

Full description

This study will use a predictive visual tracking paradigm (SyncThink EYE-SYNC eye tracking paradigm) to dynamically capture the participants' attentional state. It will examine the validity of the eye tracking paradigm in identifying the disruption in attentional networks caused by ADHD by examining the association between eye tracking performances and well-established standardized measures of ADHD.

Enrollment: 240 estimated patients

Sex: All

Ages: 6+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Men and women ages 6-70 seeking evaluation and treatment for ADHD.

Exclusion criteria

• Clinical diagnosis of a neurological condition including the following: stroke, multiple sclerosis, epilepsy, brain tumor/cancer, dyslexia, nystagmus and/or other major neurological condition.

  • Clinical diagnosis of any of the following eye-sight abnormalities: uncorrected amblyopia, uncorrected myopia, uncorrected presbyopia, uncorrected farsightedness or uncorrected Astigmatism.
  • Psychiatric history with any of the following:

• LIFETIME: Clinical diagnosis of a psychotic disorder; bipolar disorder

• LAST YEAR: Clinical diagnosis of major depressive disorder; PTSD; clinical diagnosis of substance abuse disorder; major anxiety disorder

  • Use of a psychotropic medication
  • Impairment of cranial nerves II-VI
  • Participants who receive a 'Poor' or 'Fair' eye tracking quality result on either their baseline or follow-up evaluations will be excluded from analysis. Subjects may not repeat participation

Trial design

240 participants in 4 patient groups

Adults - Diagnosis

Description:

Adults seeking treatment for an attention-related disorder

Treatment:

Device: EYE-SYNC

Adults - Prescribed

Description:

Adults who have been diagnosed with ADHD and prescribed medication treatment for the disorder

Treatment:

Device: EYE-SYNC

Children - Diagnosis

Description:

Children seeking treatment for an attention-related disorder

Treatment:

Device: EYE-SYNC

Children - Prescribed

Description:

Children who have been diagnosed with ADHD and prescribed medication treatment for the disorder

Treatment:

Device: EYE-SYNC