Oculocardiac Reflex Brain Wave Monitor (OCRBIS)

Alaska Blind Child Discovery

Status: Completed

Conditions: Bradycardia; Strabismus

Treatments: Device: non-invasive monitor

Study type: Observational

Funder types: Other

Identifiers

NCT03663413

ABCD OCR BIS

Details and patient eligibility

About

Oculocardiac reflex during routine strabismus surgery was prospectively observed in association with routine brain wave monitoring.

Providence Hospital institutional review board (IRB) approved this observational study without need for consent.

Full description

Introduction: The oculocardiac reflex (OCR), bradycardia that occurs during strabismus surgery, is blocked by anticholinergics and enhanced by opioids and dexmedetomidine. Two recent studies suggest that deeper inhalational anesthesia monitored by bispectral index (BIS) protects against OCR; the investigators wondered if our data correlated similarly.

Methods: In an ongoing, prospective study of OCR elicited by 10-second, 200 gram square-wave traction on extraocular muscles (EOM) from 2009 to 2013, anesthetic depth was estimated in cohorts using either BIS or Narcotrend monitors. The depth of anesthesia was deliberately varied between first and second EOM tested.

Enrollment: 188 patients

Sex: All

Ages: 3+ months old

Volunteers: No Healthy Volunteers

Inclusion criteria

• all

Exclusion criteria

• those receiving anticholinergic medications

Trial design

188 participants in 2 patient groups

BIS

Description:

Monitored with BIS (bispectral index) monitor in addition to other conventional monitors of blood pressure, ECG, oxygen saturation and anesthetic agent concentration.

Treatment:

Device: non-invasive monitor

Narcotrend

Description:

Monitored with Narcotrend monitor in addition to other conventional monitors of blood pressure, ECG, oxygen saturation and anesthetic agent concentration.

Treatment:

Device: non-invasive monitor