Oestrogen Withdrawal in Hypopituitary Women

University of Aarhus

Status: Completed

Conditions: Hypopituitarism

Treatments: Drug: oestrogen

Study type: Interventional

Funder types: Other

Identifiers

NCT00572390

oestrogen withdrawal

1999/4644

Details and patient eligibility

About

By exploring hormonal status in hypopituitary women during oestrogen treatment and without estrogen substitution the influence on sexhormones and organ function is estimated.

Full description

38 hypopituitary women were examinined twice. During oestrogen treatment and after 1 month estrogen withdrawal. A control group of healthy women were examined once.Antropometric data and hormonal parameters were collected.

Enrollment: 38 patients

Sex: Female

Ages: 18 to 60 years old

Volunteers: Accepts Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:

• Hypopituitarism

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: None (Open label)

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38 participants in 2 patient groups, including a placebo group

1

Placebo Comparator group

Description:

No oestrogen treatment

Treatment:

Drug: oestrogen

2

Experimental group

Description:

Oestrogen treatment

Treatment:

Drug: oestrogen