Office Hysteroscopy and 3D Power Doppler Vaginal Ultrasound in Assessment of Postmenopausal Bleeding

Cairo University (CU)

Status: Completed

Conditions: Postmenopausal Bleeding

Treatments: Procedure: 2D grey scale vaginal ultrasound; Procedure: Office hysteroscopy; Procedure: 3D power Doppler vaginal ultrasound

Study type: Observational

Funder types: Other

Identifiers

NCT02488798

62014

Details and patient eligibility

About

100 patients with postmenopausal bleeding were assessed with 2D vaginal ultrasound and 3D power Doppler ultrasound using the international endometrial tumor analysis group and office hysteroscopy with taking samples for histopathological analysis.

Full description

The aim was to compare the efficiency of the upper mentioned interventions in diagnosing the cause of postmenopausal bleeding.

Enrollment: 100 patients

Sex: Female

Ages: 47 to 64 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• 100 patients complaining of postmenopausal bleeding. Postmenopausal bleeding was defined as vaginal bleeding that occurred after at least 12 months of amenorrhea.

Exclusion criteria

• Exclusion criteria included any history of hormone administration in the last 6 months, any medical condition that might cause abnormal uterine bleeding like coagulation disorders, hypertension, cardiac disease, thyroid disorders or hepatic condition.

Trial design

100 participants in 1 patient group

postmenopausal bleeding group

Description:

100 women with postmenopausal bleeding undergoing 2D greyscale vaginal ultrasound and 3D Endometrial power Doppler and the features were classified using six different vascular patterns described by IETA group including the following patterns; single dominant vessel without branching, with branching, multiple vessels with focal origin, with multifocal origin at the myometrium-endometrium junction, scattered vessels or circular flow (Kucur et al., 2013 ). All patients then had Office hysteroscopy carried out in the outpatient clinic using vaginoscopic approach (Cooper et al., 2010). With endometrial samples from lesions or from the cavity for histopathological analysis.

Treatment:

Procedure: Office hysteroscopy

Procedure: 2D grey scale vaginal ultrasound

Procedure: 3D power Doppler vaginal ultrasound