Office Hysteroscopy in Infertility Work-out: the Role of Endometrial Hyperplasia in Southern Italian Women

University of Campania "Luigi Vanvitelli"

Status: Completed

Conditions: PCOS; Endometrial Hyperplasia; Infertility, Female

Treatments: Procedure: in-office hysteroscopy

Study type: Observational

Funder types: Other

Identifiers

NCT03965585

N.593

Details and patient eligibility

About

To assess the prevalence of endometrial hyperplasia (EH), endometrial intraepithelial neoplasia (EIN) and endometrial carcinoma between obese and not obese women undergoing IVF techniques for primary or secondary infertility.

Full description

Endometrial cancer and pre-neoplastic diseases represent the most incident gynecologic malignant pathologies found in women.1 Although diagnosed in postmenopausal patients, it can be also found in younger patients, especially when associated with some risk factors. Those include weight gain and lifestyle habits, such as consumption of fatty foods that increase estrogen levels. The positive association be- tween infertility and EC is well established. Infertile women with irregular menstrual periods, oligomenorrhea, or chronic anovulation have a risk of developing

A prospective cohort study conducted at "Fertility Center, OB/GYN Unit, Department of Woman, Child and General and Specialized Surgery, University of Campania "Luigi Vanvitelli", Naples, Italy".

Enrollment: 100 patients

Sex: Female

Ages: 18 to 45 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Women undergoing office hysteroscopy prior to IVF techniques

Exclusion criteria

• Severe comorbidities (i.e. cardiac, metabolic, neurologic diseases)

Trial design

100 participants in 3 patient groups

Primary Infertility

Description:

Women with a diagnosed primary infertility undergoing hysteroscopy before IVF.

Treatment:

Procedure: in-office hysteroscopy

Secondary Infertility

Description:

Women with a diagnosed secondary infertility undergoing hysteroscopy before IVF.

Treatment:

Procedure: in-office hysteroscopy

Recurrent miscarriages

Description:

Women with recurrent miscarriages undergoing hysteroscopy before IVF.

Treatment:

Procedure: in-office hysteroscopy