Ointment Therapy and Prevention of Cannulation-Induced Superficial Phlebitis (OT)

Komar University of Science and Technology

Status and phase: Unknown; Phase 2; Phase 1

Conditions: Phlebitis

Treatments: Drug: Nitroglycerin ointment; Drug: Clobetasol Topical

Study type: Interventional

Funder types: Other

Identifiers

NCT04685031

KomarUST

Details and patient eligibility

About

The aim of this study was to determine the effect of Clobetasol ointment with nitroglycerin ointment on the prevention of superficial phlebitis caused by cannulation. This clinical trial was conducted on 110 patients admitted to the surgical ward, in three groups of Clobetasol, nitroglycerin, and control. The data collection tools included demographic information, information about intravenous treatment and phlebitis measurement scale. In the intervention groups, after venipuncture, 1.5 cm (about 2 g) of ointment was applied in the distal part of the Angio catheter and the site was dressed with sterile gauze. In three time periods of 24, 48 and 72 hours from the time of venipuncture.

Full description

Aim: The aim of this study was to determine the effect of clobetasol ointment with nitroglycerin ointment on the prevention of superficial phlebitis caused by cannulation.

Background: Today, more than 80 to 90% of hospitalized patients receive intravenous treatment during their treatment, and more than 500 million peripheral venous catheters are placed annually, although cannulation provide numerous benefits in clinical setting, but because of its invasive feature, it can end in unpleasant outcomes such as phlebitis Method: This clinical trial was conducted on 110 patients admitted to the surgical ward, in three groups of clobetasol, nitroglycerin, and control. The data collection tools included demographic information, information about intravenous treatment and phlebitis measurement scale. In the intervention groups, after venipuncture, 1.5 cm (about 2 g) of ointment was applied in the distal part of the Angio catheter and the site was dressed with sterile gauze. In three time periods of 24, 48 and 72 hours from the time of venipuncture.

Enrollment: 110 estimated patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• must be older than 18 years old
• must be in need of hospitalization at least 72 hours
• does not state any previous allergic reaction to the ointments
• does not use any types of drug that can hurts veins (chemotherapy drugs, diazepam. amiodarone, and....)

Exclusion criteria

• active infection
• discharge from hospital sooner than 72 hours
• displacement of cannula before 72 hours

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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110 participants in 3 patient groups

nitroglycerin

Experimental group

Description:

after venipuncture, 1.5 cm (about 2 g) of ointment was applied in the distal part of the Angio catheter and the site was dressed with sterile gauze. In three time periods of 24, 48 and 72 hours from the time of venipuncture.

Treatment:

Drug: Clobetasol Topical

Drug: Nitroglycerin ointment

clobetasol

Experimental group

Description:

after venipuncture, 1.5 cm (about 2 g) of ointment was applied in the distal part of the Angio catheter and the site was dressed with sterile gauze. In three time periods of 24, 48 and 72 hours from the time of venipuncture.

Treatment:

Drug: Clobetasol Topical

Drug: Nitroglycerin ointment

routine

No Intervention group

Description:

routine nursing care