Olfactive Detection of Urothelial Carcinoma by Sniffer Dogs (OUAF)

University Hospital, Strasbourg, France

Status: Enrolling

Conditions: Urothelial Carcinoma

Treatments: Diagnostic Test: olfactory detection by dogs

Study type: Observational

Funder types: Other

Identifiers

NCT07334314

9630

Details and patient eligibility

About

The aim of this study is to estimate the sensitivity of olfactory detection of urothelial carcinomas of the bladder in urine samples by assistance dogs trained in this practice.

Enrollment: 340 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Adult (> 18 years old)
• Subject scheduled for any endourological surgery involving an initial cystoscopy, the most common of which are: transurethral resection of the bladder, transurethral resection of the prostate, internal optical urethrotomy, bladder lithoclast, ureteral stent replacement, ureteroscopy, etc. (non-exhaustive list)
• Subjects for whom a urine sample (for bacteriological or cytological testing) is planned as part of routine practice in the month prior to the procedure
• Subjects affiliated with a health insurance plan or beneficiaries of such a plan

Exclusion criteria

• Absence of signed informed consent / inability to provide the subject with informed information (emergency situations, difficulties in understanding the subject, etc.)
• Patient under guardianship, conservatorship, or judicial protection
• History of cancer other than urothelial bladder carcinoma, unless in complete remission for > 5 years
• Pregnant or breastfeeding women

Trial design

340 participants in 2 patient groups

Positive bladder tumor

Description:

Bladder tumor present during cystoscopy and confirmed by pathological examination.

Treatment:

Diagnostic Test: olfactory detection by dogs

Negative bladder tumor

Description:

No bladder tumor on cystoscopy/suspicious lesion but with negative pathological analysis

Treatment:

Diagnostic Test: olfactory detection by dogs