Omega-3 Fatty Acids in Chronic Periodontitis. (omega3)

Tatyasaheb Kore Dental College

Status and phase: Completed; Phase 4

Conditions: Chronic Periodontitis

Treatments: Drug: Placebo; Drug: Omega 3 fatty acid

Study type: Interventional

Funder types: Other

Identifiers

NCT01997853

TKDC13

Details and patient eligibility

About

Omega 3 fatty acids is one such dietary supplement, known to modulate the host response in chronic conditions like cardiovascular diseases, rheumatoid arthritis, ischemic cerebrovascular diseases, osteoporosis by producing Resolvins and protectins without showing any inadvertent effects.Addition of systemic Omega 3 Fatty Acids with SRP may enhance the therapeutic result of Chronic Periodontitis owing to host modulation & anti-inflammatory properties. If proven, this can be used as a routine treatment modality.

Enrollment: 60 patients

Sex: All

Ages: 30 to 55 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

1. Patients within age group of 30 to 55 years.
2. Systemically healthy individuals.
3. Patients with chronic generalized periodontitis (moderate and severe)according to Center for Disease Control (CDC) working group, 2007 criteria.

Exclusion criteria

1. Patients with systemic illnesses (i.e., diabetes mellitus, cancer, human immunodeficiency syndrome, bone metabolic diseases, or disorders that compromise wound healing, radiation, or immunosuppressive therapy),
2. Smoking,
3. Chronic alcoholics,
4. Pregnancy or lactation,
5. Use of Non Steroidal Anti Inflammatory Drugs, steroids or antibiotics / antimicrobials within September 2012 to August 2013,
6. Confirmed or suspected intolerance to omega 3 fatty acids,
7. Periodontal therapy done within the September 2012 to August 2013.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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60 participants in 2 patient groups, including a placebo group

Test Group

Active Comparator group

Description:

Patients with Chronic Periodontitis in Test Group were prescribed Omega 3 fatty acid tablets 300mg once daily for 12 weeks

Treatment:

Drug: Omega 3 fatty acid

Control Group

Placebo Comparator group

Description:

Patients with Chronic Periodontitis in Control Group were prescribed Placebo tablets once daily for 12 weeks

Treatment:

Drug: Placebo