Omega 3 Supplementation in Children With Non Alcoholic Fatty Liver (omega 3)

Ain Shams University

Status: Completed

Conditions: Fatty Liver

Treatments: Dietary Supplement: omega 3 fatty acids

Study type: Interventional

Funder types: Other

Identifiers

NCT04281121

MD 44/2017

Details and patient eligibility

About

this is a prospective, interventional, open-label, randomized study on the efficacy of omega 3 fatty acids supplementation in Egyptian children with non-alcoholic fatty liver disease who had been selected from nutrition and outpatient clinic at Pediatric hospital, Ain Shams University

Enrollment: 60 patients

Sex: All

Ages: 6 to 16 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

Children between 5 - 16 years old with diffusely hyper echogenic liver at ultrasonography were included in the study.

Exclusion criteria

• Patients with secondary causes of steatosis including total parenteral nutrition, drugs causing fatty liver disease for example steroids, hepatitis A, B, C, cytomegalovirus, Epstein-Barr virus infections, autoimmune liver disease, metabolic liver diseases, Wilson's disease, and alpha-1-antitrypsin deficiency.
• Patients currently taking fish oil supplements.
• Patients with systemic illness such as cardiac and kidney diseases.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Single Group Assignment

Masking: None (Open label)

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60 participants in 2 patient groups

supplemented

Active Comparator group

Description:

Life style modification, diet regimen and Omega-3 fatty acids supplementation

Treatment:

Dietary Supplement: omega 3 fatty acids

non supplemented

Active Comparator group

Description:

Life style modification and diet regimen

Treatment:

Dietary Supplement: omega 3 fatty acids