Omentectomy and Metabolic Syndrome

Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran

Status: Completed

Conditions: Morbid Obesity; Metabolic Syndrome

Treatments: Procedure: Laparoscopic Roux-en-Y Gastric Bypass; Procedure: Omentectomy

Study type: Interventional

Funder types: Other

Identifiers

NCT00923260

INCMNSZ-1486

Details and patient eligibility

About

The aim of the present study was to evaluate the additional effect of sudden visceral fat reduction by omentectomy on Metabolic Syndrome, acute phase reactants and inflammatory mediators in patients with morbid obesity undergoing Laparoscopic Roux-en-Y Gastric Bypass.

Full description

Although weight loss controls Metabolic Syndrome and reduces the level of inflammatory markers in patients with Morbid Obesity, patients may enjoy the benefit achieving metabolic control before significant weight loss occurs.

Enrollment: 24 patients

Sex: All

Ages: 20 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• BMI > 35 Kg/m2
• Metabolic syndrome diagnosed

Exclusion criteria

• Type 1 diabetes
• Uncontrolled type 2 diabetes
• Cirrhosis or active hepatitis
• Pregnancy
• Recent MI or stroke

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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24 participants in 2 patient groups

Roux-en-Y Gastric Bypass/Omentectomy

Experimental group

Description:

Laparoscopic Roux-en-Y Gastric Bypass with omentectomy

Treatment:

Procedure: Laparoscopic Roux-en-Y Gastric Bypass

Procedure: Omentectomy

Roux-en-Y Gastric Bypass alone

Active Comparator group

Treatment:

Procedure: Laparoscopic Roux-en-Y Gastric Bypass