Omentin-1 Level in Psoriatic Patients Treated With Narrowband Ultraviolet B Phototherapy Versus Acitretin

Mahmoud Ahmed Ali Ahmed

Status and phase: Completed; Phase 4

Conditions: Psoriasis

Treatments: Radiation: Narrowband Ultraviolet B; Drug: Acitretin

Study type: Interventional

Funder types: Other

Identifiers

NCT05203354

288/9/18

Details and patient eligibility

About

Studying the effects of Narrowband Ultraviolet B versus acitretin on psoriatic patients

Full description

Compare the effects of Narrowband Ultraviolet B versus acitretin on serum Omentin-1 level in psoriatic patients as case control study by dividing patients into 3 groups: group 1 include patients receive Narrowband Ultraviolet B, group II includes patients receive acitretin (0.5-1 mg/day) and control group. The duration of this study about 3 months after receving those interventions.

Enrollment: 60 patients

Sex: All

Ages: 20 to 50 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Patients of both sexes with psoriasis vulgaris.

Exclusion criteria

• • Patients with history of malignancies, renal and liver diseases.

  • Patients received NB-UVB phototherapy in the last 6 months.
  • Patients treated with methotrexate or biologic agents and any systemic treatment of psoriasis.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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60 participants in 3 patient groups

NB-UVB group

Active Comparator group

Description:

Patients who receive Narrowband ultraviolet B phototherapy

Treatment:

Radiation: Narrowband Ultraviolet B

Acitretin group

Active Comparator group

Description:

Patients who receive acitretin

Treatment:

Drug: Acitretin

Control group

No Intervention group

Description:

It includes apparently healthy people who will be compared to patients in the measurement of Omentin-1 level