Omics Sequencing of Specimen Derived From Mother-Infant-Pairs

Zhujiang Hospital

Status: Enrolling

Conditions: Breast-milk Collection; Healthy; Feces

Treatments: Other: Sample collection

Study type: Observational

Funder types: Other

Identifiers

NCT05462366

ZhujiangHFCYXZX

Details and patient eligibility

About

The investigators aim to collect breast-milk and feces from the participants, and apply culture techniques as well as omics sequencing technology to probe into the microbial and metabolomic signature of the specimens.

Enrollment: 100 estimated patients

Sex: All

Ages: Under 40 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• healthy pregnant women aged between 20y and 40y.
• Vaginal birth
• BMI<23.5 before pregnancy
• Infants' birth weight, between 2500g and 4000g.

Exclusion criteria

• gestational diabetes
• diagnosis of depressive disorder during pregnancy
• gestational hypertension
• diagnosis of other diseases during pregnancy
• Under probiotics or antibiotic treatment from 3 months prior to pregnancy till 3 months after delivery
• histrory of smoking and drinking alcohol
• history of diarrhea from 3 months prior to pregnancy till 3 months after delivery

Trial design

100 participants in 2 patient groups

Mother

Description:

healthy mothers

Treatment:

Other: Sample collection

Infant

Description:

healthy infants

Treatment:

Other: Sample collection