Omitting Drains After Repair of Peptic Ulcer Perforations

Cairo University (CU)

Status: Completed

Conditions: Peptic Ulcer Perforations

Treatments: Other: Using intraabdominal drains; Other: Omitting of usage of intraabdominal drains after repair of peptic ulcer perforations

Study type: Interventional

Funder types: Other

Identifiers

NCT06084741

N-79-2023

Details and patient eligibility

About

. This study aimed to evaluate ERAS application outcomes via omitting the intraabdominal drains compared to regular using of the drains in patients undergoing perforated duodenal ulcer repairs in emergency abdominal surgeries.

Full description

Patients will be randomly assigned into two groups. In Group A : the investigators will put intraabdominal drains, and in Group ,thd investigators will not put any intraabdominal drains. Our primary outcomes will be hospital stayl engthand pain score;Data analysis packages will be SPSS version 21 Qualitative data will be presented by number and percentage, quantitative data by mean, standard deviation, median and interquartile range.

Enrollment: 100 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

- Patients older than 18 years with perforated peptic ulcer who underwent exploratory laparotomy or laparoscopy and repair with omental pedicle techniques will included in the study.

Exclusion criteria

• preoperative shock on admission.

  • Delayed presentation more than 24 hours.
  • known malignant gastric ulcers confirmed by histopathology.
  • the presence of neuropsychiatric disease, pregnant and lactating women.
  • predisposing factors for impaired wound healing (e.g., currently using immunosuppressive agents, or chronic use of steroids), the presence of HIV/AIDS.
  • Intraoperative findings consistent with malignant ulcers. • American Society of Anesthesiologists grade III/IV, or had an alternative perioperative diagnosis. • Ulcer size more than 2 cm in diameter.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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100 participants in 2 patient groups

Drain group

Active Comparator group

Description:

In Group A the investigators will put intraabdominal drains

Treatment:

Other: Using intraabdominal drains

No drain group

Experimental group

Description:

The investigators will not put any intraabdominal drains

Treatment:

Other: Omitting of usage of intraabdominal drains after repair of peptic ulcer perforations