On Demand Treatment of Reflux Disease

Norwegian University of Science and Technology

Status and phase: Completed; Phase 4

Conditions: Gastroesophageal Reflux

Treatments: Drug: esomeprazole; Drug: Aflurax

Study type: Interventional

Funder types: Other; Industry

Identifiers

NCT00184522

SLV 02-01973

Details and patient eligibility

About

A comparison of the effect of on demand treatment with a pectin-containing natural product (Aflurax) with that esomeprazole (Nexium)

Full description

A randomized, controlled, open trial comparing the symptomatic effect of a pectin-containing product (Aflurax) with that of esomeprazole (Nexium 20 mg) given on-demand for 6 weeks.

Enrollment: 82 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

Mild and moderate reflux symptoms Age > 17 years Informed consent -

Exclusion criteria

Other conditions that might explain the symptoms Abuse of drugs or alcohol

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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82 participants in 2 patient groups

Aflurax

Experimental group

Description:

pectin-containing natural product

Treatment:

Drug: Aflurax

esomeprazole (Nexium)

Active Comparator group

Description:

esomeprazole (Nexium)

Treatment:

Drug: esomeprazole