On Dose Efficiency of Modern CT-scanners in Chest Scans

U

University Hospital Augsburg

Status

Completed

Conditions

Pulmonary Embolism
Pulmonary Disease
Lung Cancer
Pneumonia
Aortic Stenosis

Treatments

Diagnostic Test: CT Scan using an Energy-Integrating Detector CT (128 slice MDCT)
Diagnostic Test: CT Scan using an Energy-Integrating Detector CT (20-slice MDCT)
Diagnostic Test: Imaging on Scanner with Spectral Imaging Capabilities

Study type

Interventional

Funder types

Other

Identifiers

NCT04996693
21-0368

Details and patient eligibility

About

CT scans of the chest / thorax are of great importance both in the initial diagnosis and in the follow-up of pulmonary or thoracic diseases. As an example, CT angiography of the pulmonary arteries (CTPA) is worldwide considered to be gold standard test in patients with a suspicion for pulmonary embolism. The aim of this study is to measure and compare dose efficiency of modern CT scanners for unenhanced and contrast-enhanced scan protocols of the chest/thorax. Patients who are referred for a CT of the chest/thorax will be randomly assigned to one of the three CT scanners currently in use at our institution.

Enrollment

958 patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • patient is referred for an unenhanced CT OR contrast-enhanced CT of the chest/thorax confirmed by a board-certified radiologist ('justifying indication' according to German/European radiation protection law) AND
  • patient is at least 18 years of age AND
  • patient (is able to give informed consent and) has given informed consent.

Exclusion criteria

  • high degree of medical urgency (i.e. patient cannot be consented for iv contrast according to routine procedures)
  • known or suspected pregnancy, or lactating . contraindications for contrast agent (renal failure, allergy, hyperthyroidism)

Trial design

Primary purpose

Diagnostic

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

None (Open label)

958 participants in 3 patient groups

Scanner 1
Other group
Description:
Imaging performed on scanner 1: Photon-Counting Detector CT
Treatment:
Diagnostic Test: Imaging on Scanner with Spectral Imaging Capabilities
Scanner 2
Other group
Description:
Imaging performed on scanner 2: Energy-Integrating Detector CT (128-slice)
Treatment:
Diagnostic Test: CT Scan using an Energy-Integrating Detector CT (128 slice MDCT)
Scanner 3
Other group
Description:
Imaging performed on scanner 3: Energy-Integrating Detector CT (20-slice)
Treatment:
Diagnostic Test: CT Scan using an Energy-Integrating Detector CT (20-slice MDCT)

Trial contacts and locations

0

Loading...

Central trial contact

Florian Schwarz, MD

Data sourced from clinicaltrials.gov

Clinical trials

Find clinical trialsTrials by location

Resources

© Copyright 2024 Veeva Systems