Once Daily vs Twice Daily Administration of Gonadotropins in Assisted Reproductive Technologies (ART) (QD vs BID)

Virginia Center for Reproductive Medicine

Status: Completed

Conditions: Pregnancy

Study type: Observational

Funder types: Other

Identifiers

NCT00740025

1-Sharara

Details and patient eligibility

About

This is a prospective randomized study evaluating dosing frequency of gonadotropin administration in ART cycles.

Full description

Using once daily or bid dosing of gonadotropins in ART has been arbitrary with no studies showing whether splitting the medication dose improves ART parameters. This study was undertaken to provide an answer to this important question.

Enrollment: 200 estimated patients

Sex: Female

Ages: 21 to 39 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• women < 40 undergoing ART

Exclusion criteria

• women > 40
• endometriomas
• severe cervical stenosis
• testicular sperm

Trial design

200 participants in 2 patient groups

QD

Description:

Women who received their meds as QD administration

BID

Description:

Women who received their gonadotropins as a BID dose