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Oncologic Outcomes Based on Clinical Pattern of Preoperative PET-CT in Resected Pancreatic Cancer

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Yonsei University

Status

Completed

Conditions

Pancreatic Cancer

Treatments

Device: PET-CT

Study type

Observational

Funder types

Other

Identifiers

NCT03077334
4-2014-0702

Details and patient eligibility

About

The 18F-FDG-PET scan is currently being used for cancer diagnosis, staging, identifying hidden metastasis, and assessment of treatment responses in clinical oncology. Although there are important studies suggesting potential associations between PET-based parameters and oncologic outcomes, the calculation and official documentation of individual PET-based parameters might not be routine in clinical practice because these processes usually require time- and labor-consuming processes for the radiologists. In this study, the investigators prospectively determined clinical 18F-FDG-PET type according to degree of FDG-uptake in pancreatic cancer and compare oncologic outcomes between the types.

Enrollment

200 patients

Sex

All

Ages

20 to 80 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Candidate for radical pancreatectomy due to pancreatic cancer without neoadjuvant treatment
  • Age between 20 years old and 80 years old
  • General performance status greater than 70
  • Results of peroperative PET-CT available

Exclusion criteria

  • Unresectable, locally advance and metastatic pancreatic cancer
  • Patients not wanting operation
  • ASA score of greater than 3
  • History of chronic alcoholism ot drug abuse
  • Lack of patient compliance
  • Patients not agreeing to enroll in the study.
  • Patients unable to understand and sign the study agreement.
  • History of neoadjuvant treatment

Trial design

200 participants in 2 patient groups

K-type
Description:
FDG uptake in pancreatic cancer is similar to that of kidney
Treatment:
Device: PET-CT
non K-type
Description:
FDG uptake in pancreatic cancer is lower than that of kidney
Treatment:
Device: PET-CT

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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