One-shot Ovarian Stimulation Protocol (One-shot)

Fundación Santiago Dexeus Font

Status: Enrolling

Conditions: Infertility, Female

Treatments: Diagnostic Test: Monitoring cycle; Drug: Corifollitropin alfa (CFA) 150 mcg + Clomiphene Citrate (CC) 100 mg/day from D1; Drug: Clomiphene Citrate (CC) 100 mg/day from D1

Study type: Interventional

Funder types: Other

Identifiers

NCT06635538

FSD-ONE-2024-09

Details and patient eligibility

About

The current prospective observational pilot study aims to evaluate the endocrine profile of a single-injection protocol (single CFA + daily oral administration of CC).

Enrollment: 20 estimated patients

Sex: Female

Ages: 18 to 40 years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:

Age <= 40

AMH (Anti-Mullerian Hormone) 1.2-3.5 ng/ml or AFC 7-20

No family history of hereditary or chromosomal diseases

Body mass index (BMI) 18 to 30 kg/m2

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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20 participants in 1 patient group

Corifollitropin alfa (CFA) 150 mcg + Clomiphene Citrate (CC) 100 mg/day from D1

Experimental group

Treatment:

Drug: Clomiphene Citrate (CC) 100 mg/day from D1

Drug: Corifollitropin alfa (CFA) 150 mcg + Clomiphene Citrate (CC) 100 mg/day from D1

Diagnostic Test: Monitoring cycle