One-Year Outcomes After Conversion Bariatric Surgery

Medipol University

Status: Active, not recruiting

Conditions: Revisional Bariatric Surgery; Obesity & Overweight; Bariatric Surgery

Study type: Observational

Funder types: Other

Identifiers

NCT07345429

MUDU-SBE-SS-01

Details and patient eligibility

About

Obesity is a growing global public health problem, and bariatric surgery is currently the most effective treatment for achieving sustained weight loss and improving obesity-related comorbidities. However, a subset of patients experience inadequate weight loss or weight regain following primary bariatric surgery, which may lead to the recurrence of metabolic complications and reduced quality of life. In such cases, conversion bariatric surgery, defined as the surgical conversion from one bariatric procedure to another, is considered an important therapeutic option. Despite the increasing number of conversion procedures, comprehensive longitudinal data evaluating anthropometric, biochemical, and nutritional outcomes after conversion bariatric surgery remain limited.

This study aims to prospectively evaluate individuals undergoing conversion bariatric surgery due to weight regain following primary bariatric surgery. Anthropometric measurements, biochemical parameters, and nutritional status will be assessed preoperatively and at 1 year after surgery. By evaluating weight loss outcomes together with metabolic and nutritional changes, this study seeks to provide clinically relevant evidence to guide postoperative follow-up strategies, optimize nutritional management, and support multidisciplinary care in patients undergoing conversion bariatric surgery.

Enrollment: 14 estimated patients

Sex: All

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Adults aged 18-45 years
• Previously underwent bariatric surgery
• Subsequently underwent conversion bariatric surgery due to suboptimal clinical response

Suboptimal clinical response defined as either:

• Suboptimal Clinical Response (SCR): maximum total weight loss (TWL%) of <20% within 18 months after metabolic and bariatric surgery
• Recurrent Weight Gain (RWG): regaining >30% of initial postoperative weight loss after achieving initial weight reduction

Exclusion criteria

• Pregnancy or lactation
• Presence of acute illness or infection
• Comorbid conditions that could limit treatment efficacy or compromise safety
• Participation in professional athletic activity

Trial design

14 participants in 1 patient group

Conversion Bariatric Surgery

Description:

This cohort includes patients who previously underwent conversion bariatric surgery as part of routine clinical care and were followed observationally. Anthropometric measurements, biochemical parameters, and nutritional status were assessed at the preoperative period and postoperative month 12 (1 year).