Online Adaptive Radiotherapy Using a Novel Linear Accelerator (ETHOS) (ART-02)

Charité University Medicine Berlin logo

Charité University Medicine Berlin

Status

Enrolling

Conditions

Bladder Cancer
Esophageal Cancer
Rectum Cancer
Other Carcinoma
Head and Neck Cancer
Prostate Cancer
SCLC
Cervix Cancer
NSCLC

Treatments

Radiation: Online adaptive radiation therapy

Study type

Observational

Funder types

Other

Identifiers

NCT06116019
3000902

Details and patient eligibility

About

The study focuses on the scientific and clinical evaluation of online adaptive radiotherapy (ART) using the Varian/SHS ETHOS treatment system. In this study, radiation treatment plans are dynamically adjusted on a daily basis over several weeks of therapy to account for anatomical shifts in either the tumour or adjacent normal tissue - a capability that has been difficult to achieve due to technical limitations. With the ETHOS accelerator, such real-time adjustments can be made based on cone beam computed tomography (CBCT). This is a prospective observational study with the primary objective of investigating the feasibility and acceptability of performing ART with ETHOS for different tumour entities. The study will also evaluate the feasibility of integrating multi-parametric data sets into the ART workflow, such as standardised electronic feedback on treatment toxicity from both patients (ePROMS) and physicians (ePRT).

Enrollment

649 estimated patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Adult patients (>18 years)
  • All tumor entities with an indication for radiotherapy and/or chemoradiotherapy
  • Signed informed consent

Exclusion criteria

  • Pregnancy
  • Patients who are not capable of giving consent

Trial contacts and locations

0

Loading...

Central trial contact

Goda Kalinauskaite, MD; Carolin Senger, MD

Data sourced from clinicaltrials.gov

Clinical trials

Find clinical trialsTrials by location

Resources

© Copyright 2024 Veeva Systems