Online Hemodiafiltration Versus Hemodialysis in Removal of Indoxyl Sulfate in Chronic Hemodialysis Patients

Ain Shams University

Status: Completed

Conditions: Hemodialysis

Treatments: Procedure: low flux hemodialysis; Procedure: online hemodiafiltration; Procedure: high flux hemodialysis

Study type: Interventional

Funder types: Other

Identifiers

NCT05771350

FMASU MD 301/2016

Details and patient eligibility

About

this study aimed to compare the removal of indoxyl sulphate between hemodiafiltration, high flux hemodialysis and low flux hemodialysis

Enrollment: 60 patients

Sex: All

Ages: 18 to 75 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• maintenance hemodialysis patients aged more than 18 years

Exclusion criteria

• active illnesses, hospitalization, malignancy

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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60 participants in 3 patient groups

online hemodiafiltration

Experimental group

Treatment:

Procedure: online hemodiafiltration

high flux hemodialysis

Active Comparator group

Treatment:

Procedure: high flux hemodialysis

low flux hemodialysis

Active Comparator group

Treatment:

Procedure: low flux hemodialysis