Online Yoga and the Impact on Psychosis

The Royal Ottawa Mental Health Centre

Status: Unknown

Conditions: Psychosis

Treatments: Behavioral: Yoga; Behavioral: Mindfulness

Study type: Interventional

Funder types: Other

Identifiers

NCT05046912

2021021

Details and patient eligibility

About

Yoga and mindfulness are considered complementary and alternative healthcare options that involve breathing techniques, relaxation, and bodily postures (yoga only). Research has shown a positive effect of these on depression, quality of life, and other symptoms of psychosis. As an 8-week pilot study, the goal is to offer yoga and/or mindfulness online and to explore the effect on recovery and quality of life for people with psychosis.

Full description

Psychosis impacts about 3% of Canadians at any given time. People with psychosis can experience a combination of positive (e.g., delusions; hallucinations), negative (e.g., amotivation; reduced social activity), or cognitive symptoms (e.g., poorer memory; executive functioning). Positive symptoms are managed via antipsychotic medication and therapeutic support; cognitive symptoms can be targeted via cognitive remediation therapy. For negative symptoms, especially those idiopathic, there are still no effective care options. Yoga is a complementary and alternative medicine (CAM) encompassing health modalities of Eastern cultures, it involves breathing techniques, relaxation, and bodily postures. Research has shown that yoga can improve levels of depression and quality of life, and even attenuate negative symptoms. Given the extensive health care expenditures and unmet care needs for negative symptoms, there is a growing need to consider CAMs, such as yoga, and accessibility of CAMs via online methods. As a pioneering study, this proposed pilot study aims to explore the effect of an 8-week (i.e., 8 sessions) online yoga program on recovery/outcome, with a focus on negative symptoms, for people with psychosis. The investigators aim to recruit 24 people with psychosis and randomly assign them to either the yoga (n=12) or a mindfulness group (n=12); mindfulness, in essence, is yoga without the physical aspect (i.e., poses). The investigators hypothesize that yoga will improve quality of life and attenuate symptom severity, with a larger effect on negative symptoms, above the effect of mindfulness. A nonclinical sample (n=12) will also be recruited to examine feasibility and for feedback purposes.

Enrollment: 36 estimated patients

Sex: All

Ages: 18 to 85 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

For clinical participants:

• primary diagnosis of a schizophrenia-spectrum disorder (schizophrenia, schizophreniform, schizoaffective) or related psychotic disorder (delusional, brief psychotic, paraphrenia, bipolar with psychotic features, major-depressive with psychotic features)
• access to protected internet (i.e., home internet plugged or password protected wireless)
• adequate space to do yoga (e.g., at least 2 feet around each side of the yoga mat)
• able to speak and read English
• competent and able to offer voluntary informed consent to participate

For non-clinical participants (healthy controls):

• not diagnosed with or received care for any mental illness
• access to protected internet (i.e., home internet plugged or password protected wireless)
• adequate space to do yoga (e.g., at least 2 feet around each side of the yoga mat)
• able to speak and read English
• competent and able to offer voluntary informed consent to participate

Exclusion criteria

For clinical participants:

• not clinically stable; that is, major change in primary medication (e.g., switching or stopping antipsychotic) or hospitalisation within the past 4 weeks prior to first contact
• currently with a physical ailment that restricts light movement exercises for yoga or chair yoga

For non-clinical participants (healthy controls):

• have a first-degree relative with psychosis (schizophrenia, schizo-affective, schizophreniform, paraphrenia, brief psychotic, delusional, or bipolar or major depressive disorder with psychotic features)
• had a substance or alcohol abuse/dependence in the past 6 months
• currently with a physical ailment that restricts light movement exercises for yoga or chair yoga

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

---

36 participants in 2 patient groups

Clinical

Experimental group

Description:

Clinical participants with a primary diagnosis of psychosis or related disorder.

Treatment:

Behavioral: Yoga

Behavioral: Mindfulness

Non-clinical

Active Comparator group

Description:

Non-clinical participants with no mental health diagnoses.

Treatment:

Behavioral: Yoga

Behavioral: Mindfulness