Oocyte Recipient's Decision in the Number of Embryos to be Transferred

Institut Universitari Dexeus

Status: Completed

Conditions: Decision Making; Counseling; Infertility, Female

Treatments: Behavioral: Oral and written counselling

Study type: Interventional

Funder types: Other

Identifiers

NCT03185715

SMD-2014-121

Details and patient eligibility

About

Multiple pregnancies are considered an ART complication. The only effective way to reduce its incidence is to transfer a single embryo. Nonetheless, there is some reluctance among the patients to accept this strategy. In IVF/ICSI programs, it has been demonstrated that, after receiving the information about the similar cumulative live birth rate after single embryo transfer (SET) and double embryo transfer (DET) and the obstetric and perinatal risks of multiple pregnancy, a significant number of patients opt for SET. Up to date, no comparable studies have been published in oocyte recipients. The aim of this study is to evaluate if the information given to the patients influence their preference on the number of embryos to be transferred. It also seeks to identify factors which determine the initial preference and factors which can explain a hypothetic change in this preference.

Enrollment: 100 patients

Sex: Female

Ages: 18 to 50 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Patients under their first oocyte or embryo donation cycle.
• Sufficient knowledge of Spanish to fill out questionnaires.

Exclusion criteria

• Patients with a medical indication for single embryo transfer (e.g. Turner syndrome, uterine surgeries, cardiovascular risk).
• Having had previous oocyte or embryo donation cycles.
• Insufficient knowledge of Spanish.

Trial design

Primary purpose: Other

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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100 participants in 1 patient group

Counseling policy embryo transfer

Other group

Description:

All recipients completed a validated self-report questionnaire on the preference on the number of embryos to be transferred and the relevance for the decision-making process attributed to certain factors. The questionnaire also included questions on sociodemographic characteristics, medical-reproductive background and cycle's results and risks perception. All recipients received oral and written counselling. After counselling, during the treatment, the recipients completed a second questionnaire in order to check if their decision had changed.

Treatment:

Behavioral: Oral and written counselling