Open Lung Approach Versus Standard Protective Strategies

Fundación para la Investigación del Hospital Clínico de Valencia

Status: Completed

Conditions: Lung Collapse

Treatments: Procedure: OLA; Procedure: RM-5

Study type: Interventional

Funder types: Other

Identifiers

NCT02798133

OLA

Details and patient eligibility

About

The aim of this study was to compare the effects of adding a recruitment maneuver (RM) to low tidal volume (VT) ventilation, with or without an individualized post-RM positive end-expiratory pressure (PEEP) setting in lung-healthy patients during anesthesia.

Enrollment: 36 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• ASA physical status I-III undergoing elective major abdominal surgery including pancreatic-duodenectomy, gastrectomy and liver resection

Exclusion criteria

• i) laparoscopic surgery, ii) patients with previous respiratory disease.

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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36 participants in 2 patient groups

OLA

Experimental group

Description:

recruitment maneuver + individualized PEEP

Treatment:

Procedure: OLA

RM-5

Active Comparator group

Description:

recruitment maneuver + fixed standard PEEP

Treatment:

Procedure: RM-5