Open Lung PEEP in Thoracic Surgery

Fundación para la Investigación del Hospital Clínico de Valencia

Status: Completed

Conditions: Ventilation Therapy; Complications; Thoracic Surgery

Study type: Observational

Funder types: Other

Identifiers

NCT03184974

PEEPOPTIMA

Details and patient eligibility

About

During thoracic surgical procedures, while ventilating with a protective tidal volume, an open lung approach consisting of a recruitment maneuver followed by an individualized positive end-expiratory pressure (PEEP) titrated to best respiratory system compliance (Open-lung PEEP, OL-PEEP) would decrease driving pressure. To test this hypothesis, we performed a multicenter observational study in 17 Spanish teaching hospitals of patients undergoing one lung ventilation (OLV). In addition, we analyzed the association between the driving pressure and the prevalence of postoperative pulmonary complications (PPCs), and finally the association between the individualized PEEP and relevant patient preoperative or intraoperative variables.

Enrollment: 690 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients undergoing one lung ventilation

Exclusion criteria

• No exclusion criteria