Open Versus Laparoscopic Left Hepatic Sectionectomy

The Second Hospital of Anhui Medical University

Status: Unknown

Conditions: Enhanced Recovery; Laparoscopic Liver Resection; Hepatolithiasis; Open Liver Resection

Treatments: Procedure: open left hepatic sectionectomy; Procedure: laparoscopic hepatic sectionectomy

Study type: Interventional

Funder types: Other

Identifiers

NCT03958825

520

Details and patient eligibility

About

Laparoscopic left sectionectomy has been associated with shorter hospital stay and reduced overall morbidity compared with open left sectionectomy. Strong evidence has not, however, been provided.

Full description

The application of laparoscopic technology to liver surgery has been developing rapidly, yet very few studies have been conducted to compare the outcomes between open and laparoscopic liver resections. So little is known about their advantages and disadvantages. The aim of this prospective randomized study is to compare the outcomes between laparoscopic and open liver resection in treatment of hepatolithiasis within the left lobes within an enhanced recovery after surgery programme.

Enrollment: 88 estimated patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients suitable for undergoing both laparoscopic left sectionectomy as well as open left sectionectomy of the liver
• Able to understand the nature of the study and what will be required of them
• Men and non-pregnant,non-lactating women between age 18-80
• BMI between 18-35
• Patients with ASA I-II-III

Exclusion criteria

• Inability to give written informed consent
• Patients undergoing liver resection other than left lateral hepatic sectionectomy
• Patients with ASA IV-V Underlying liver disease

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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88 participants in 2 patient groups

open left hepatic sectionectomy

Active Comparator group

Description:

patients undergoing open left hepatic sectionectomy within an enhanced recovery after surgery programme

Treatment:

Procedure: open left hepatic sectionectomy

laparoscopic hepatic sectionectomy

Experimental group

Description:

patients undergoing a laparoscopic left hepatic sectionectomy within an enhanced recovery after surgery programme

Treatment:

Procedure: laparoscopic hepatic sectionectomy