Opioid Free Pterygopalatine Ganglion Block Based Multimodal Anesthesia for Tonsillectomy Operations

Ain Shams University

Status: Completed

Conditions: DECREASE POSTTONSILLECTOMY NAUSEA AND VOMITTING; DECREASE POSTOPERATIVE HOSPITAL STAY; PREVENTION OF POSTTONSILLECTOMY PAIN

Treatments: Procedure: pterygopalatine ganglion block based multimodal anesthesia); Procedure: opioid based multimodal anesthesia

Study type: Interventional

Funder types: Other

Identifiers

NCT05513209

IRB00006379 TON

Details and patient eligibility

About

intraoperative opioid administration versus intraoperative pterygopalatine ganglion block based opioid free anesthesia to compare outcomes such as postoperative administration of opioid rates of nausea and vomiting, Post Anesthesia Care Unit (PACU) length of stay

Full description

Group A ;( opioid based multimodal anesthesia) One hundred and twenty pediatric patients will do elective tonsillectomy or adenotonsillectomy surgery using opioid based multimodal anesthesia.

Group B ;( opioid free pterygopalatine ganglion block based multimodal anesthesia) One hundred and twenty pediatric patients will do elective tonsillectomy or adenotonsillectomy surgery using opioid free pterygopalatine ganglion block based multimodal anesthesia.

For each patient, intraoperative hemodynamics, additional intraoperative analgesia required, the length of PACU stay, administration of postoperative opioids, administration of postoperative non-opioid analgesics, postoperative (visual analogue score) VAS score, will be recorded.

Enrollment: 90 patients

Sex: All

Ages: 4 to 13 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age 4 to 13 years old.
• Elective tonsillectomy or adenotonsillectomy surgery

Exclusion criteria

• Allergies to xylocaine.
• Developmental delays.
• Significant cognitive impairment.
• American Society of Anesthesiologists (ASA) Class 3 and 4.
• Patients who underwent any additional concurrent procedures such as lingual tonsillectomy.

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

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90 participants in 2 patient groups

opioid based multimodal anesthesia

Active Comparator group

Description:

One hundred and twenty pediatric patients will do elective tonsillectomy or adenotonsillectomy surgery using opioid based multimodal anesthesia.

Treatment:

Procedure: opioid based multimodal anesthesia

opioid free pterygopalatine ganglion block based multimodal anesthesia

Active Comparator group

Description:

One hundred and twenty pediatric patients will do elective tonsillectomy or adenotonsillectomy surgery using opioid free pterygopalatine ganglion block based multimodal anesthesia.

Treatment:

Procedure: pterygopalatine ganglion block based multimodal anesthesia)