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Opioid Reduction Toolkit Reduces Opioids Prescribed and Consumed

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Thomas Jefferson University

Status and phase

Suspended
Phase 4

Conditions

Opioid Abuse
Pain
Opioid Misuse

Treatments

Drug: Oxycodone

Study type

Interventional

Funder types

Other

Identifiers

NCT05363436
19D.688Panc

Details and patient eligibility

About

Investigators studied a baseline population of patients receiving pancreatectomies at their institution and determined how many opioid pills each patient was prescribed and how many they took. Based on this data they created a toolkit to provide to prescribers to give patients a modified number of pills. The amount prescribed and consumed was measured after intervention.

Full description

A single academic surgical department reviewed opioid treatment patterns for patients undergoing common procedures, including open pancreatectomy, and an opioid reduction toolkit using the data collected was created. Providers were educated on the use of the toolkit and it was implemented as a standard of practice. Data were collected on pancreatectomy patients via telephone interview (performed at 2 weeks post-op) and by reviewing the state prescription drug monitoring program. Outcome variables included morphine milliequivalents (MME) of pills prescribed, MME of pills consumed, number of patients aware of proper unused pill disposal, number of patients requesting refills, and pain scores. Categorical and continuous outcomes were compared within and between groups.

Enrollment

159 patients

Sex

All

Ages

18 to 99 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Age > 18
  • Being scheduled for an outpatient elective pancreatectomy

Exclusion criteria

  • Urgent/emergent status
  • Concomitant procedure being performed at time of pancreatectomy

Trial design

Primary purpose

Prevention

Allocation

Non-Randomized

Interventional model

Parallel Assignment

Masking

None (Open label)

159 participants in 2 patient groups

Control
No Intervention group
Description:
Normal Standard Practices of Prescribing
Intervention
Experimental group
Description:
Providers prescribed a base of 15 narcotic pills
Treatment:
Drug: Oxycodone

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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