Opioid Sparing Potential of Light-Induced Analgesia

Duke University

Status: Completed

Conditions: Pain

Treatments: Device: Blue Light; Device: Clear light; Device: Green light

Study type: Interventional

Funder types: Other

Identifiers

NCT03890419

Pro00102106

Details and patient eligibility

About

This is a pilot trial testing the potential opioid-sparing analgesic effect of a novel non-pharmacological treatment using visualized light spectrums. Preclinical findings have shown such treatments to alter pain perception.

Enrollment: 94 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Scheduled for thoracic surgery for which post-operative opioid PCA is anticipated (Acute Pain group) OR currently treated with opioid therapy for fibromyalgia (Chronic Pain group)
• 18 years of age and older
• Able to wear study eyeglasses for at least 4 hours per day
• Agree to participate and provide written informed consent and HIPAA authorization

Exclusion criteria

• None

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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94 participants in 3 patient groups

Control Group

Active Comparator group

Description:

Control Group participants will be exposed to full spectrum light during the study.

Treatment:

Device: Clear light

Green light Group

Experimental group

Description:

Green light Group participants will be exposed to green light during the study.

Treatment:

Device: Green light

Blue light Group

Experimental group

Description:

Blue light Group participants will be exposed to blue light during the study.

Treatment:

Device: Blue Light