Opioid vs. Opioid-free Anesthesia for Hip Arthroscopy

Clinica Santa Maria

Status and phase: Terminated; Phase 3

Conditions: Postoperative Analgesia; Opioid Free Anaesthesia

Treatments: Drug: Lidocaine/ ketamine; Drug: Fentanyl

Study type: Interventional

Funder types: Other

Identifiers

NCT02150161

56csm2014001

Details and patient eligibility

About

The purpose of this study is to determine whether an infusion of lidocaine/ketamine compared to fentanyl is equivalent in anesthesia effectiveness and can help reduce the incidence of postoperative nausea and vomiting in patients undergoing elective hip arthroscopy surgery.

Enrollment: 53 patients

Sex: All

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• 18-65 years old
• ASA I-II
• Undergoing elective hip arthroscopy

Exclusion criteria

• Known allergies to study drugs
• Opioid use 1 month prior to surgery
• BMI >30
• Unable to comprehend visual analog scale

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

---

53 participants in 2 patient groups

lidocaine/ ketamine infusion

Experimental group

Description:

lidocaine 1mg/Kg bolus, followed by continuous infusion 1 mg/kg/h AND ketamine 1mg/Kg bolus followed by continuous infusion 1 mg/kg/h

Treatment:

Drug: Lidocaine/ ketamine

fentanyl

Active Comparator group

Description:

iv fentanyl, 3ug/kg bolus

Treatment:

Drug: Fentanyl