Optic Nerve and Retinal Functions With Bevacizumab

Cairo University (CU)

Status: Completed

Conditions: Choroidal Neovascular Membrane

Treatments: Procedure: Electrophysiology

Study type: Observational

Funder types: Other

Identifiers

NCT01361828

Beva-ERG-VEP

Details and patient eligibility

About

The purpose of this study is to investigate the possible affection of optic nerve and retinal functions following intravitreal bevacizumab injection in human eyes.

Full description

To evaluate the retinal and optic nerve functions of bevacizumab when injected intravitreal in human eyes using electrophysiological tests; Electroretinogram (ERG) and Visual Evoked Potentials (VEP). Forty five eyes of 45 patients with choroidal neovascular membrane (CNV) who were prepared for intravitreal injections of 1.25mg bevacizumab underwent baseline ERG and VEP in both eyes before, and at 1 and 4 weeks after the intravitreal injections.

Enrollment: 45 patients

Sex: All

Ages: 24 to 62 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• CNV

Exclusion criteria

• Previous Intravitreal Injections

Trial design

45 participants in 1 patient group

Patients with choroidal neovascularization

Description:

CNV due to Age-Related Macular Degenerations and Myopia were included.

Treatment:

Procedure: Electrophysiology