Optic Nerve Sheath After Extracorporeal Circulation

University Medical Centre Maribor

Status: Completed

Conditions: Cardiac Disease; Cardiac Valve Disease

Treatments: Diagnostic Test: MoCA test; Diagnostic Test: ultrasound measurement of the optic nerve sheath diameter

Study type: Observational

Funder types: Other

Identifiers

NCT05335902

UKC-MB-KME-59/21

Details and patient eligibility

About

The purpose of this study is to assess the influence of extracorporeal circulation during cardiac surgery on the optic nerve sheath diameter (ONSD) after the surgery.

Full description

ONSD will be measured before and 1 hour after the surgery and in the morning of day 1 after the surgery. Fluid balance and lactate will be measured too. PONV will be assessed. Patients will be evaluated with MoCA test on the day before surgery and on the day 3 after the surgery for cognitive disfunction.

Enrollment: 100 patients

Sex: All

Ages: 18 to 90 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• heart surgery with use of cardiopulmonary bypass

Exclusion criteria

• pregnancy and lactation
• neurologic disorders
• hyperthyroidism
• optic nerve disorders

Trial design

100 participants in 2 patient groups

standard cardiopulmonary bypass

Description:

patients 18 year or older undergoing heart surgery with standard cardiopulmonary bypass

Treatment:

Diagnostic Test: ultrasound measurement of the optic nerve sheath diameter

Diagnostic Test: MoCA test

mini-cardiopulmonary bypass

Description:

patients 18 year or older undergoing heart surgery with standard mini-cardiopulmonary bypass

Treatment:

Diagnostic Test: ultrasound measurement of the optic nerve sheath diameter

Diagnostic Test: MoCA test