Optic Nerve Sheath Diameter: A Non-Invasive Indicator of Intracranial Pressure in the Intensive Care Unit Monitoring

Istanbul University - Cerrahpasa (IUC)

Status: Completed

Conditions: Optic Nerve Sheath Diameter; Intracranial Hypertension; ICP (Intracranial Pressure) Increase

Treatments: Procedure: After 5 ml CSF Drainage

Study type: Interventional

Funder types: Other

Identifiers

NCT06367868

E-83045809-604.01.02-179951

Details and patient eligibility

About

Determination of high intracranial pressure (ICP) is necessary for the treatment of patients with raised ICP to improve long-term neurological outcomes. Ultrasonographic optic nerve sheath diameter (ONSD) measurement is a noninvasive, easily performed and cost effective technique for detecting high ICP.

Full description

ICP measurements via ventricular catheters provide CSF drainage and ICP reduction. The normal ICP value is less than 15 mmHg in adults. In the literature the correlation of ONSD and invasive ICP measurements were determined. The aim of study is to evaluate the correlation of ONSD and direct ICP measurements and to determine cut off ONSD value to detect ICP ≥15 mmHg.

Enrollment: 44 patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• 18-80 aged patients
• With an external ventricular drainage catheter due to intracranial pathology

Exclusion criteria

• Under the age of 18
• Orbital tumors
• Graves' disease
• Exophthalmos
• Sarcoidosis
• Optic neuropathy
• Meningitis
• Ocular trauma
• Lung diseases

Trial design

Primary purpose: Diagnostic

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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44 participants in 1 patient group

Before Drainage

Experimental group

Description:

Optic nerve sheath diameter and intracranial pressure will be measured before CSF drainage

Treatment:

Procedure: After 5 ml CSF Drainage