Optic Nerve Sheath Diameter in Preeclampsia

Kanuni Sultan Suleyman Training and Research Hospital

Status: Completed

Conditions: Pre-Eclampsia

Treatments: Diagnostic Test: Optic nerve sheath diameter measurement

Study type: Interventional

Funder types: Other

Identifiers

NCT04004897

Huseyin3

Details and patient eligibility

About

Severe preeclampsia is associated with an elevation in intracranial pressure (ICP). Optic nerve sheath diameter is a non-invasive surrogate of invasive ICP measurement. This study targets to evaluate the ICP in patients with or without preeclampsia.

Full description

MRI studies have shown that brain edema due to an elevation in ICP develops in up to 70% of women with preeclampsia. Optic nerve sheath diameter is used to estimate the ICP and has been shown to correlate well with invasive ICP measurement. The present study aims to compare ICP using optic nerve sheath diameter in women with or without preeclampsia.

Enrollment: 90 patients

Sex: Female

Ages: 18 to 49 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Must be diagnosed as preeclampsia
• Age must be > 18 years

Exclusion criteria

• History of previous intracranial pathology or surgery
• Glaucoma

Trial design

Primary purpose: Diagnostic

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

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90 participants in 2 patient groups

Preeclampsia group

Other group

Description:

Patients with preeclampsia will receive optic nerve sheath diameter measurement with a linear ultrasound probe carefully and gently placed on the closed upper eyelids of patients.

Treatment:

Diagnostic Test: Optic nerve sheath diameter measurement

Pregnants without preeclampsia

Other group

Description:

Pregnant women without preeclampsia will receive optic nerve sheath diameter measurement with a linear ultrasound probe carefully and gently placed on the closed upper eyelids of patients.

Treatment:

Diagnostic Test: Optic nerve sheath diameter measurement