Optical Coherence Tomography Guided Percutaneous Coronary Intervention for Drug-eluting In-stent Restenosis

Chinese PLA General Hospital (301 Hospital)

Status

Unknown

Conditions

CHD - Coronary Heart Disease

Percutaneous Coronary Intervention

In-stent Restenosis

Treatments

Procedure: Percutaneous Coronary Intervention under Angiography

Procedure: Percutaneous Coronary Intervention under OCT

Study type

Interventional

Funder types

Other

Identifiers

NCT03809754

Z171100001017158

Details and patient eligibility

About

This study is a prospective, registry trial aimed to compare the clinical and angiographic outcomes of OCT-guided and angiography-guided PCI in patients with coronary DES-ISR.

Enrollment

240 estimated patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Age 18 years or older
Patients with angina or evidence of myocardial ischaemia
Patients with restenotic lesions in a previously DES area of a coronary artery
Patients suitable to receive any types of percutaneous coronary intervention (including balloon angioplasty and stent implantation)
The stent diameter of DES-ISR is 2.5mm to 4.0mm
Target lesion length < 30mm
Target lesion stenosis ≥ 70% diameter stenosis on visual assessment, or ≥ 50% diameter stenosis and with evidence of myocardial ischaemia ischemic

Exclusion criteria

Patients with acute myocardial infarction with 1 week
Patients with evidence of extensive thrombosis in the target vessel
Patients with left main coronary artery disease
Patients with cardiogenic shock, left ventricular ejection fraction < 40%,significant renal dysfunction and severe heart valve disease
Patients who had cerebral stroke within 6 months before PCI
Patients with a life expectancy < 1 year
Patients not able to adhere to follow-up visits