Optical Coherence Tomography in Retinal Vein Occlusion

Assiut University

Status: Not yet enrolling

Conditions: Optical Coherence Tomography (OCT)

Study type: Observational

Funder types: Other

Identifiers

NCT06886893

OCT in retinal vein occlusion

Details and patient eligibility

About

This study aims to evaluate how optical coherence tomography (OCT) can help predict outcomes in patients with retinal vein occlusion (RVO), a condition that affects blood flow in the retina. RVO can cause macular edema, which is swelling in the part of the eye responsible for central vision. The study will use OCT scans to assess changes in the retina and how these changes relate to vision improvement over time.

Full description

Objectives Evaluate how OCT data can predict visual outcomes by analyzing retinal changes and macular edema characteristics.

Assess the correlation between baseline OCT biomarkers and visual acuity improvements over time.

Study Design Type: Cross-sectional study.

Setting: Conducted at several eye care centers in Egypt.

Participants Inclusion Criteria: Adults with branch or central RVO, macular edema confirmed by OCT, and no prior RVO in the affected eye.

Exclusion Criteria: Other retinal diseases, recent intraocular surgery, or significant media opacities.

Procedures Informed Consent and History Taking.

Ophthalmologic Examination: Includes BCVA, IOP, slit-lamp biomicroscopy, and fundus examination.

OCT Imaging: Using NIDEK RS-330 Retina scan duo 2 (SD-OCT) to assess macular changes.

OCT Image Evaluation: Classification of macular edema types and assessment of biomarkers like subretinal fluid and cystoid changes.

Enrollment: 30 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Adults aged 18 years or older.

Patients diagnosed with branch or central retinal vein occlusion.

Patients with macular edema confirmed by OCT due to vein occlusion.

Patients with no prior history of RVO in the affected eye.

Exclusion criteria

• Presence of other retinal diseases that could affect OCT interpretation (e.g., diabetic retinopathy, age-related macular degeneration).

History of intraocular surgery within the last three months.

Presence of significant media opacities (e.g., dense cataract, vitreous hemorrhage) that interfere with OCT imaging.

Trial design

30 participants in 1 patient group

Adults with branch or central RVO, macular edema confirmed by OCT, and no prior RVO in the affected

Description:

Adults aged 18 years or older. Patients diagnosed with branch or central retinal vein occlusion. Patients with macular edema confirmed by OCT due to vein occlusion. Patients with no prior history of RVO in the affected eye.