Optical Coherence Tomography of Nerve Fiber Layer and Ganglion Cell Complex After Cataract Extraction

Kasr El Aini Hospital

Status: Completed

Conditions: Cataract; Primary Open-angle Glaucoma

Treatments: Diagnostic Test: Oct scans

Study type: Observational

Funder types: Other

Identifiers

NCT03889652

N-68-2018

Details and patient eligibility

About

Optical coherence tomography (OCT) for retinal nerve fiber layer (RNFL) and ganglion cell complex (GCC) is done before and after cataract extraction in patients with or without primary open angle glaucoma (POAG)

Full description

The investigator's study includes two groups of patients, each consists of 25 eyes, group 1 (cataract group)includes patients who are planned for cataract extraction without any other preexisting retinal or optic nerve pathology that may affect the RNFL thickness, while group 2 (combined cataract and glaucoma group) includes patients who are diagnosed with POAG controlled on medical treatment with cataract and planned for cataract extraction only.

The OCT scans with complete ophthalmological examination are done before surgery and 6 weeks after uneventful cataract extraction (phacoemulsification with intraocular lens implantation)

Enrollment: 48 patients

Sex: All

Ages: 50+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• patients with cataract without any other concomitant retinal, optic nerve head pathology other than POAG are included in the study and divided onto two groups

Exclusion criteria

• Patients having any retinal or optic nerve pathology that might have affected nerve fiber layer thickness other than POAG eg: high myopia
• POAG patients who are planned for combined surgery
• Refractive errors greater than spherical equivalent of 6 diopters (myopia or hypermetropia)
• Dense cataract hindering OCT imaging
• History of previous ocular surgery or trauma

Trial design

48 participants in 2 patient groups

Cataract group

Description:

Group 1 includes patients who are planned for cataract extraction without any other preexisting retinal or optic nerve pathology that may affect the RNFL thickness. OCT (investigation) before and after cataract extraction

Treatment:

Diagnostic Test: Oct scans

Combined cataract and glaucoma group

Description:

Group 2 includes patients who are diagnosed with POAG controlled on medical treatment and have cataract and planned for cataract extraction only OCT is done before and after cataract extraction

Treatment:

Diagnostic Test: Oct scans