Optical Coherence Tomography of Tear Film Dynamics In-Vivo

University of Rochester

Status

Completed

Conditions

Dry Eye Disease

Treatments

Other: Optical Coherence Tomography

Study type

Interventional

Funder types

Other

Identifiers

NCT02554084

52165

Details and patient eligibility

About

The purpose of this study is to evaluate a new instrument that takes digital images of tear film (a thin film that coats the eye that is made up of oil and water). The investigators are interested in measuring how the thickness of the tear film varies through time. The goal is to develop a technique that may enable non-invasive evaluation of Dry Eye Disease for future clinical diagnosis.

Enrollment

2 patients

Sex

All

Ages

18+ years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

Clinically diagnosed Dry Eye Disease
Normal individuals (those without a dry eye diagnosis and without eye abnormalities)
Good general health (defined by medication use that has not changed within the last month and the absence of medical conditions that are deemed confounding to the data as determined by the PI)
Ability to give informed consent
Willing to spend time for the study
Either gender
Any racial or ethnic origin

Exclusion criteria

Use of any prescription ocular medication (such as but not limited to, glaucoma medications and Restasis) used within 14 days of the study visit
Current eye disease, infection or inflammation that affects the surface of the eye such as, but not limited to blepharitis and ocular allergy
Past eye surgery, such as, but not limited to, refractive surgery. Subjects who have had cataract surgery less than one year ago
Use of soft or hard contact lenses 6 hours prior to visit
Female subjects may not be pregnant or lactating (subjects will be asked to self-report these conditions)
Infectious diseases (for example, hepatitis, tuberculosis) or an immuno-suppressive disease (for example, HIV) (subjects will be asked to self-report these conditions)