Optical Coherence Tomography Quantitative Analysis of Changes in Anterior Chamber After Laser Peripheral Lridotomy

Central South University

Status: Unknown

Conditions: Primary Angle Closure Glaucoma

Treatments: Procedure: Laserex Tango Nd:YAG, Ellex-SuperQ Medical, Australia

Study type: Interventional

Funder types: Other

Identifiers

NCT02279472

SecondXHCSU

Details and patient eligibility

About

The purpose of this study is to analysis changes in anterior segment morphology after laser peripheral lrldotomy measured by optical coherence tomography, and to evaluate treatment effectiveness

Full description

In the study ,primary angle closure(PAC) and primary angle closure glaucoma (PACG) will be recruited. Anterior segment optical coherence tomography images captured before and after laser peripheral iridotomy will be analysed to provide objective and reproducible quantification of anterior segment biometric parameters.The outcomes can provide useful information for clinical strategies in the treatment and management of pathology related to angle closure.

Enrollment: 40 estimated patients

Sex: All

Ages: 30 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1 .The gonioscopy or UBM examination has confirmed the diagnosis of PACS or PAC 2. Intraocular pressure within 10 to 21 mmHg ，C/D≤0.6 3. Visual field is normal or only show paracentral scotoma 4. Vision or corrected visual acuity ≥0.8 5. Refractive degree no more than 200D 6. Exclude other ocular and systemic diseases

Exclusion criteria

1. Corneal macula and other corneal diseases, ocular surface disease or corneal edema
2. Iridocyclitis
3. Ocular trauma and intraocular operation history
4. No fixationFundus lesions such as diabetic retinopathy or retinal detachment
5. No fixation
6. Ocular or systemic application of cortical steroids -

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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40 participants in 1 patient group

laser peripheral iridotomy

Other group

Description:

Laser peripheral iridotomy (LPI) is widely regarded as the first-line intervention for either acute or chronic types of angle-closure glaucoma in early stage ,which relieves pupil block and thus flattening the iris contour and widening the drainage angle,performd by Nd.YAG LASER

Treatment:

Procedure: Laserex Tango Nd:YAG, Ellex-SuperQ Medical, Australia