Optical Elastography of Systemic Sclerosis Skin

The University of Texas System (UT)

Status: Completed

Conditions: Scleroderma

Treatments: Other: Visual Assessment; Device: Optical Elastography

Study type: Observational

Funder types: Other

Identifiers

NCT02835196

PR150338 (Other Grant/Funding Number)

HSC-MS-16-0383

Details and patient eligibility

About

The goal of this study is to develop a new way to assess skin thickness in patients with scleroderma (systemic sclerosis). The study will test how well a new imaging method called optical coherence elastography (OCE) compares to the current clinical method used to estimate skin thickness, the modified Rodnan Skin Score (mRSS).

Enrollment: 12 patients

Sex: All

Ages: 18 to 75 years old

Volunteers: Accepts Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria for scleroderma patients:

• meet the 2013 American College of Rheumatology and the European League Against Rheumatism (ACR/EULAR) criteria for systemic sclerosis with limited or diffuse cutaneous involvement

Exclusion Criteria:

• have another skin disease other than systemic sclerosis

Trial design

12 participants in 2 patient groups

Optical Elastography Assessment of Skin Thickness

Treatment:

Device: Optical Elastography

Visual Assessment of Skin Thickness

Treatment:

Other: Visual Assessment